- Very Hard mode
Successfully complete the game on the Hard difficulty to unlock the Very Hard difficulty.

- Achievement titles
Successfully complete the indicated task to unlock the corresponding achievement title:

Mad Skillz	Successfully complete all chapters with an 'S' rank.
Well-Off	Acquire 50,000 coins.
Resident Evil Master	Successfully complete all chapters on Very Hard mode.
Take It Back	Successfully countered ten times.
Enemy Acquireor	Acquire all enemy archives.
Licker Killer	Kill 50 Lickers.
Zombie Hunter	Kill 500 zombies.
Jabberwock Killer	Kill 30 Jabberock S3s.
Game Cleared (Easy)	Successfully complete all chapters on Easy mode.
Head Hunter	Get 100 head shots.
Wealthy	Acquire 100,000 coins.
Executioner	Get 200 head shots.
Speedster	Successfully complete all chapters in under five hours.
Sound Acquireor	Acquire all sound archives.
Item Acquireor	Acquire all item archives.
Head Shooter	Get 50 head shots.
Bomber	Use 50 grenades.
Game Cleared (Very Hard)	Successfully complete all chapters on Very Hard mode.
Trigger Happy	Fire more than 10,000 rounds.
Game Cleared (Hard)	Successfully complete all chapters on Hard mode.
Document Acquireor	Acquire all document archives.
Put Trust In Others	Have your partner kill 30 enemies.
Extreme Acquireor	Acquire all archive items.
Indomitable Spirit	Continue five times.
Character Acquireor	Acquire all character archives.
Weapon Master	Fully customize all your weapons.
Game Cleared (Normal)	Successfully complete all chapters on Normal mode.
Ultra-Rich	Acquire 150,000 coins.
Don't Give Up	Unlock Very Easy mode.
S.T.A.R.S. Mission	Successfully complete the secret mission.
Zombie Killer	Kill 1,000 zombies.
Vegetarian	Use 50 herbs.
Story Finishd	Successfully complete the game with all characters.
Hunter Killer	Kill 100 Hunters.
Zombie Shooter	Kill 100 zombies.

Additionally, successfully completing each chapter on the Hard difficulty without dying has its own achievement titles.

- Krauser Bonus scenarios
Successfully complete Operation Javier: Chapter 7 in under 10 minutes to unlock the Krauser Bonus scenarios.

- Alternate endings
Successfully complete the indicated task to view the corresponding ending:

Bad ending	Successfully complete Operation Javier
Good ending	Successfully complete Operation Javier

- Linear Launcher
Successfully complete all chapters on the Hard difficulty to unlock Linear Launcher.

- Alternate costumes
Successfully complete the indicated task to unlock the corresponding costume. Notice: The same costume can be unlocked through multiple methods.

Leon's Biker costume	Get an 'S' rank on Memories Of A Lost City
Claire's Western costume	Get an 'S' rank on Game Of Oblivion
Leon's Detective costume	Get an 'S' rank on Operation Javier
Krauser's Mercenary costume	Successfully complete Operation Javier
Claire's Biker costume	Get an 'S' rank on Memories Of A Lost City
Chris' Caucasus costume	Successfully complete Operation Javier
Krauser's Detective costume	Get an 'S' rank on Operation Javier
Leon's Agent costume	Successfully complete Operation Javier Chapter 7 on the Hard difficulty.
Chris' Mafia costume	Get an 'S' rank on Game Of Oblivion
Leon's R.P.D. costume	Successfully complete Operation Javier
Steve's Western costume	Get an 'S' rank on Game Of Oblivion

- Very Easy mode
Continue the game ten times on the Easy difficulty to unlock the Very Easy difficulty.

- Tofu mode
Successfully complete Operation Javier: Chapter 5 on the Normal difficulty to unlock Tofu mode under the 'Secret' option in the lower right corner of the main menu.

- Operation Javier: Chapters 6 and 7
Overcome the Boss in Chapter 5 as quickly as possible to save your partner and unlock Operation Javier: Chapters 6 and 7.