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New Game+ mode
Successfully complete the game on any difficulty to unlock New Game+ mode. This mode allows you to begin a second playthrough with all your weapons, items, and inventory from the previous game.
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Re-spec ability
At the begin of Chapter 7, you will have the option to re-spec your weapons, RIG, and stasis module. This ability allows you to take out all the power nodes in a piece of equipment and re-assign them elsewhere. Each time you re-spec an item, it will cost 5000 CR. This ability does not help you get the achievement for upgrading all your equipment, but it is helpful to re-assign (or take back) power nodes from weapons you do not use anymore. Additionally, you can use this ability to refill Isaac's health at any workbench. If you re-spec the RIG, any changes to a health node will reset Isaac's health to the new maximum. For 5,000 credits, a re-spec is cheaper than a large medikit.
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Hidden Necromorph messages
Use the Right Analog-stick to look around the following menu areas to find the following hidden messages:
Main menu
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| Upper left | 'In the end, it all comes down to just one little thing...' |
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| Bottom right | 'Unity after death, unity forever.' |
Single Player menu
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| Upper left | 'Your body now, our body later, one body forever' |
Multiplayer menu
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| Upper middle | 'It's not over between us, you can't run from me forever' |
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| Bottom middle | 'Make us Whole' |
Quick Match menu
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| Bottom right | 'We must believe in it and bend ourselves to its will and then it will heal us' |
Leaderboard menu
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| Right | 'The answer is in chicxulub' |
Extra menu
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| Left | 'Welcome back Nicole Brennan' |
Controller Map menu
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| Bottom right | 'Let us fear nothing. Death is only a transition to the unity beyond' |
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Easy credits
Purchase the Supernova or Martial Law DLC. Then, go to the store, and purchase the Detonator weapon for free. Fire all the mines at a wall, then deactivate them and collect them. Do not reload the Detonator. Sell the mines and Detonator for credits at the store. Buy the Detonator back for free, and it will be fully stocked. Repeat this process as many times as desired.
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Prequel bonuses
Have a saved game file from the original Dead Space to begin the game with access to the Refurbished Plasma Cutter. However, your upgrades to the Plasma Cutter from Dead Space will not carry over.
Successfully complete Dead Space: Ignition in single player Ignition mode to unlock the Hacker Suit (has bonus perks and hacking capabilities), a Hacker-themed Contact Beam weapon skin, exclusive audio logs, and extra power nodes, health packs, and credits.
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Multiplayer unlockables
Reach the indicated level in Multiplayer mode to unlock the corresponding bonus:
| Urban Camo Army Green Suit | Level 23 |
| Tiger Camo Army Green Suit | Level 45 |
| Urban Camo Red Suit | Level 26 |
| Force Gun Weapon Damage Increase | Level 46 |
| Pack Execution Attack Damage Increase | Level 18 |
| Urban Camo Military | Level 32 |
| War Torn Suit | Level 56 |
| Seeker Rifle Damage Increase | Level 50 |
| Force Gun Magazine Size Increase | Level 29 |
| Plasma Cutter Magazine Size Increase | Level 14 |
| Solid Army Green Suit | Level 4 |
| Pack Gets Out of Stasis Faster | Level 48 |
| Solid Red Suit | Level 8 |
| Tiger Camo Military Suit | Level 52 |
| Spitter Ranged Damage Increase | Level 35 |
| Javelin Gun | Level 28 |
| Line Gun Weapon Damage Increase | Level 42 |
| Solid Black Suit | Level 13 |
| Pack Health Increase | Level 31 |
| Stasis Increase to 2 Shots | Level 5 |
| Tiger Camo Blue Suit | Level 41 |
| Puker Execution Attack Damage Increase | Level 24 |
| Lurker Range Damage Increase | Level 3 |
| Lurker Health Increase | Level 43 |
| Tiger Camo Red Suit | Level 49 |
| Lurker Execution Attack Damage Increase | Level 27 |
| Puker Melee Damage Increase | Level 39 |
| Urban Camo Blue Suit | Level 20 |
| Spitter Melee Damage Increase | Level 21 |
| Rivet Gun Magazine Size Increase | Level 40 |
| Line Gun | Level 7 |
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| Seeker Rifle Magazine Size Increase | Level 33 |
| Spitter Health Increase | Level 53 |
| Spitter Execution Damage Increase | Level 9 |
| Javelin Gun Magazine Size Increase | Level 44 |
| Plasma Cutter Weapon Damage Increase | Level 34 |
| Javelin Gun Weapon Damage Increase | Level 57 |
| Puker Health Increase | Level 58 |
| Pulse Rifle Weapon Damage Increase | Level 38 |
| Seeker Rifle | Level 17 |
| Solid Olive Suit | Level 16 |
| Lurker Melee Damage Increase | Level 15 |
| Puker Ranged Damage Increase | Level 12 |
| Line Gun Magazine Size Increase | Level 25 |
| Urban Camo Olive Suit | Level 36 |
| Force Gun | Level 11 |
| Rivet Gun Weapon Damage Increase | Level 54 |
| Pulse Rifle Magazine Size Increase | Level 19 |
| Stasis Increase to 3 Shots | Level 30 |
| Pack Melee Damage Increase | Level 6 |
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| Visceral Games Suit | Level 59 |
Additionally, you can unlock the Solid Viral Blue Suit, Solid Viral White Suit, Tiger Camo Viral White Suit, Urban Camo Viral Black Suit, and Urban Camo Viral Yellow Suit by killing a player that is wearing them. The Zealot Suit comes with the Acquireor's Edition of the game.
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Bonus suits
Successfully complete the game on any difficulty to unlock bonus elite suits in New Game+ mode. During a second playthrough, the Riot Armor Suit will be available in the store. The Elite Engineer Suit schematic can be found in Chapter 2 near the first store, just before the first short outer space section. The Elite Vintage Suit schematic can be found in Chapter 6 in the large hallway where Ellie and Stross are talking to you from the balcony and you are attacked by a Brute (it is next to a statue near the wall). The Elite Security Suit schematic can be found in Chapter 9 after exiting the tram with Ellie the first time; search over the railing to your right to find it on the floor. The Elite Advance Suit schematic can be found in Chapter 11 when the yellow lift that the Necromorphs jump onto reaches the top, turn around, and it is on the ledge between the elevator and wall.
Successfully complete the game on the Hardcore difficulty to unlock the Soldier Suit at the store. Successfully complete the game on the Zealot difficulty to unlock the Arctic Security Suit at the store.
Log into your same EA account through the Dead Space iOS game to unlock the Riot Armor Suit. This suit gives a weapon bonus to the Contact Beam of 10% extra damage and has 25 inventory slots and 25% armor.
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Hardcore mode
Successfully complete the game on any difficulty to unlock the Hardcore difficulty. This difficulty is equivalent to the Zealot difficulty, but only allows you to rebegin from the last saved game. It also only allows you to save three times during the entire campaign, and cannot be begined from a New Game +.
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Skipping the Drag Tentacle in Chapter 5
During the Drag Tripod encounter in the Church of Unitology, pause the game and rebegin from the checkpoint to skip the entire sequence and go straight to the Pack encounter.
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Achievements
Do the following things to obtain the corresponding Gamerscore points:
| 10 Points |
| C-Section | Knock down an enemy with Contact Beam Alt-Fire then kill it with Primary Fire before it stands up. | | | Lightspeed de Milo | Dismember the Lightspeed Boy Statue. | | | Brute Juke | Kill a Brute without taking damage. | | | The Nanny | Kill 30 Crawlers without detonating them. | | | Bouncing Betty | Kill a Cyst by catching its Mine and throwing it back. | | | Looking good | Purchase the Advanced Suit. | | | The Engineer | Acquire 10 Schematics. | | | Lawnmower Man | Kill 4 enemies with the same Ripper blade. | | | The Librarian | Acquire 100 logs. | | | Necro FlambāŠ | Kill 50 enemies using the Flamethrower. | | | Made Us Whole | Finish the game on any difficulty setting. | | | The Electrician | Acquire 10 Semiconductors. | | | 15 Points | | Skewered in Space | Impale an enemy into a Decompression Be victorious indow to cause it to blow out. | | | Think Fast | Kill 30 Necromorphs with Kinesis objects. | | | 20 Points | | Taste of your own Medicine | TK Impale a live Slasher to a surface using a Slasher's arm - it must stick to the surface. | | | Peek a Boo! | Kill a Stalker with the Seeker Rifle while in Zoom Mode. | | | Going for Distance | Impale an enemy and make him fly through the air for 17 meters - it must stick to the surface. | | | Acquire Peng | Find the Peng treasure. | | | It's a Trap! | Kill 20 enemies with Detonator Mines in a deployed state. | | | 25 Points | | Romper Stomper | Stomp 10 Containers. | | | 30 Points | | Fully Outfitted | Improve your RIG and Stasis completely. | | | Vacuum Cleaner | Decompress 20 Necromorphs without getting sucked out yourself. | | | Picking favorites | Improve 1 Weapon completely. | | | 50 Points | | Fully Loaded | Simultaneously have four completely upgraded weapons. | | | Hard to the Core | Finish the game on Hard Core setting. | | | Mission Impossible | Finish the game on Zealot setting. | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| 10 Points |
| One Small Step | Get through the first Zero-G area. | | | Clever Girls | Survive your first encounter with Stalkers. | | | Shut Down | Overcome the AI. | | | 15 Points | | Elevator Action | Knock off every Tripod during the Elevator Sequence. | | | Patient on the Loose | Get your first Suit. | | | Operation! | Snare the Shard with the Ishimura. | | | Powered Up | Finish the Solar Array Puzzle. | | | 20 Points | | The Graduate | Be victorious in the fight at the School. | | | Derailed | Survive the Train Sequence. | | | Torment Me No More | Kill the Tormenter. | | | 25 Points | | Knock Knock | Finish the Drill Ride. | | | 30 Points | | Hornet's Nest | Destroy the Tripod Nest. | | | Cross your Heart, Hope to Die | Survive the Eye Poke Machine. | | | 50 Points | | The Final Sacrifice | Destroy the Marker. | | | The Fugitive | Escape the Facility. | | | | | | | | | | | | | | | | |
| 20 Points |
| Peng Me Again | Severed | | | Grind House | Severed | | | Remember the Alamo | Severed | | | King of the Hill | Severed | | | 50 Points | | The Veteran | Severed | | | | | | |
| 20 Points |
| Ship Shape | Severed | | | 50 Points | | The Betrayal | Severed | | | The Sacrifice | Severed | | | | |
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