Modes and Unlockables
- New Game+: complete the game on any difficulty. You restart the story on any difficulty keeping all the upgrades and evolutions of the previous playthroughs.
- Insane Difficulty: complete the game on any difficulty.
How to Find the Upgrades
To get an upgrade you have to consume the target's DNA. If you accidentally kill one of these targets, they come back to life randomly, and sometimes in different places. It is best to complete the main missions and the BlackNet ones, then fly over the streets in a helicopter to find the remaining targets, moving from one island to the next. You can also enter the coordinates shown on the in-game map.
Power
- Blades: coordinates 904, 1440 (Green Zone, Lincoln Meadows, mission "Taking the Castle") and 903, 1440 (same area, mission "Fall from Grace").
- Claws: 112, 1337 (Yellow Zone, Linden Park, first Blackwatch mission); 834, 1182 (Green Zone, Lincoln Meadows, a Juggernaut in the last cell of the lair).
- Hammerfists: 627, 146 (Red Zone, Times Square, a Brawler in the street); 563, 280 (Red Zone, Midtown, after "Last Resort", a Brawler in the street).
- Tendrils: 449, 1146 (Yellow Zone, Oakhurst: do not let the scientist reach the Green Zone); 359, 1443 (mission "Natural Selection").
- Whipfists: mission "Blackwatch Stronghold 9-D"; 568, 132 (Red Zone, Times Square, after "Last Resort"); 549, 115 (Times Square, after "Labor of Love", a Brawler).
Abilities
- Armor: 924, 1274 (Green Zone, Lincoln Meadows: after the first lair, the soldiers on the helipad); 490, 600 (Red Zone, Chinatown, on top of the Blackwatch Stronghold near the helipad).
- Helicopters: 474, 890 (Red Zone, Downtown, soldier on top of the Blackwatch Stronghold); 756, 195 (Red Zone, Midtown, after "Last Resort").
- Launchers: 327, 1295 (Yellow Zone, Oakhurst, "Operation Flytrap"); 883, 1281 (Green Zone, "Air Bridge"); 492, 852 (Red Zone, Downtown, in the Blackwatch Stronghold near the ocean).
- Rifles: 405, 1341 (Yellow Zone, Linden Park, "Operation Flytrap"); entering the Lincoln Meadows lair; 729, 604 (Red Zone, Chinatown, on the floor of the Blackwatch Stronghold).
- Bio-Bomb: mission "Alpha Wolf" (Green Zone); 346, 223 (Red Zone, Midtown, inside the first lair); 508, 267 (Midtown, a Brawler on the ground or on the arena roof); 652, 278 (Midtown, after "Blackwatch", a Brawler in the street).
- Pack Leader: 477, 255 and 646, 239 (Red Zone, Midtown); 613, 431 (Chinatown, after "Last Resort"); Times Square (after "Last Resort").
- Shield: defeat Roland in the mission "A Nest of Vipers".
The 9 Lairs
A contamination symbol appears near each lair. Destroying them all gives the "Spindler's Search" achievement.
- Yellow Zone, Linden Park: lair 1, 407, 1344 (alley between the buildings; you enter after the Green Zone).
- Green Zone: lair 2, 835, 1181 (Lincoln Meadows, small park); lair 3, 841, 1485 (alley between the apartments); lair 4, 702, 1278 (Fulton, alley between the buildings); lair 5, 720, 1331.
- Red Zone: lair 6, 372, 217 (Midtown, near the harbor); lair 7, 664, 225 (Midtown, near a building covered by the Virus); lair 8, 568, 130 and lair 9, 661, 110 (Times Square, near infected buildings).
Achievements (Gamerscore)
- 100 points: Murder Your Maker? (complete the game).
- 50 points: Finally Full (all 46 upgrades with consumes), All Growed Up (fully upgrade Heller), Master Prototype (complete the game on Hard difficulty).
- 40 points: Spindler's Search (destroy all the lairs), //BLACKNET Hacker (complete all the BlackNet dossiers).
- 30 points: Eating Your Way to the Top (30 upgrades with consumes), The Mad Scientist (complete "Natural Selection"), Something to Live For (complete "Fall from Grace"), What a Bitch (complete "Labor of Love"), Follow Your Nose (all the Black Boxes), Up to No Good (defeat all the Field Ops teams).
- 20 points: Anger Management (5 vehicles destroyed with a Terminator), So Above It All (25 consecutive seconds in the air, helicopters excluded), One by One (stealthily consume 50 Blackwatch soldiers), Wanted Man (50 alarms), This Is a Knife (first Prototype Power), Project Closed (one BlackNet mission), Do the Evolution (5 mutations), All Together Now (10 kills with a single Black Hole attack), Back Atcha! (send back 5 missiles with the Shield), Two for the Price of One (2 Brawlers with a single Devastator), Hard to Please (one mutation for each of the 5 categories), Who Watches the Watchers? (consume 10 BlackNet targets), Sic 'Em! (5 helicopters destroyed with the Pack Leader), Over-Equipped (10 vehicles used as weapons), The Best Offense (20 counterattacks with the Shield), Road Rage (10 tanks, APCs or helicopters with a single hijacked vehicle).
- 15 points: Icarus (reach the highest point in the world), Lair to Rest (destroy a lair), Hijack Be Nimble (5 tanks or APCs hijacked silently), The Floor Is Lava (half a mile without touching the ground, with wall runs, jumps, air dashes and glides).
- 10 points: Vitamin B-rains (10 upgrades), It's an Epidemic, I Want Some More, Religious Experience (meet Father Guerra), Strike, You're Out (destroy an assault squad in 15 seconds), Compulsive Eater (5 consumes in 10 seconds), Just a Flesh Wound (dismember a Brawler), Cannonball! (20 kills with a single Hammerfist), You're the Bomb (10 kills with a single Bio-Bomb), Arcade Action (hit a helicopter with a karate kick), I Caught a Big One! (mount a helicopter with the whip).



















